E-ISSN : 2733-4538
This experiment used electric shock as stressor and observed effects of ranitidine (a H₂-receptor antagonist) and lorazepam(a minor tranquilizer) on inhibiting the development of stomach lesion, administrating each one or together. A total of 32 rats were put in Skinner Box and received electric shocks for 48 hours. They were randomly assigned to each of the four groups, that is, a lorazepam. a ranitidine, a ranitidine+lorazepam, and a control group. Results show that the group administrated lorazepam exhibited significantly less stomach lesion than the other groups. There was no group difference in terms of bodyweight-loss, lever pressing and water drinking except for the index of stomach lesion.